TABLE OF CONTENTS

Rok
Lista numerów

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Spis treści/Contens

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Overview of regulatory initiatives in the European Union to stimulate research and accelerate access to orphan drugs and other high medical need products

Aleksandra Baran-Kooiker, Coen Kooiker, Marcin Czech WIĘCEJ

Determination of fluconazole and its oxidation products with kinetic evaluation under potassium per-manganate treatment in acidic solutions by ultra performance liquid chromatography-tandem mass spectrometry

Urszula Hubicka, Jan Krzek, Paweł Żmudzki, Barbara Żuromska-Witek, Dariusz Motyl, Agata Kryczyk WIĘCEJ

Purity determination of the starting materials used in the synthesis of pharmaceutical substances

Aleksandra Groman, Elżbieta Stolarczyk, Mariola Mucha WIĘCEJ

Development and validation of RP-HPLC method for simultaneous quantification of sulfacetamide sodium and prednisolone sodium phosphate

Nabiha Abdullah, Fizza Karamat, Shaista Qamar, Mateen Abbass, Abdul Muqeet Khan, Naseem Ullah WIĘCEJ

Development and validation of stability-indicating hplc method for diflucortolone valerate and isoconazole nitrate combination

Suriye Özlem Gündogdu, Funda Şimşek, Asuman Doganay, Yilmaz Çapan WIĘCEJ

Formulation and in vivo pharmacokinetic studies of iloperidone depot injection

Vineet Dubey, Tulsi Ram Saini WIĘCEJ

Bioavailability of mesalazine from two coated formulation tablets

Franciszek K. Główka, Tadeusz W. Hermann, Jacek Hermann, Maciej Zabel WIĘCEJ

Effects of bee venom on activity and expression of 15-lipoxygenase-1 in human HT29 colon cancer

Mohammad Soukhtanloo, Maryam Zare, Jina Khayatzadeh, Hamidreza Sadegh Nia, Majid Mojarad, Fatemeh Baghbani, Javad Sargolzaei, Hamid Sadeghian, Mohsen Sisakhti WIĘCEJ

From harvesting to distillation - effect of analytical procedures on the yield and chemical composition of Rho-dodendron tomentosum (Ledum palustre) essential oil

Anna Jesionek, Bożena Zabiegała, Adam Buciński, Maria Łuczkiewicz WIĘCEJ

Chemical profile and antibacterial activity of essential oils from leaves and fruits of Gaultheria procumbens L. cultivated in Poland

Anna Magiera, Monika Sienkiewicz, Monika A. Olszewska, Agnieszka Kicel, Piotr Michel WIĘCEJ

Use of glutaric acid to improve the solubility and dissolution profile of glipizide through pharmaceutical cocrystallization

Fakhra Batool, Mahmood Ahmad, Muhammad Usman Minhas, Fahad Mehmood Khan, Hafiz Arfat Idrees, Qandeel Khalid WIĘCEJ

Seleno-L-methionine modulate the toxic effect of new doxorubicin metal complexes in prokaryotic model - Escherichia coli RMF recA::lux

Marzena Matejczyk, Grzegorz Świderski, Włodzimierz Lewandowski WIĘCEJ

Sildenafil upregulates tumor necrosis factor a production in peripheral blood mononuclear cells of healthy men - preliminary report

Beata Kaleta, Agnieszka Boguska, Jan Borysowski, Andrzej Górski WIĘCEJ

Population pharmacokinetics of 25-hydroxy vitamin D in non- elderly postmenopausal women

Jelena Djokovic, Aleksandra Tomic Lucic, Olivera Z. Milovanovic, Danijela Bazic, Mirjana Veselinovic, Ale-ksandar Djukic, Sandra Matovic, Radica Zivkovic Zaric, Radmila Velickovic Radovanovic, Slobodan M. Jankovic, Jasmina R. Milovanovic WIĘCEJ

Cocaine consumption in the city of Murcia (southeast of Spain) estimated by wastewater analysis: applying an accurate and valid tool to obtain objective data for drug abuse

Lucía Fernández-López, Javier Navarro-Zaragoza, Francisco Caravaca, María Falcón, Aurelio Luna WIĘCEJ

The effects of sulfur-containing compounds on redox status in homocysteine-treated rats

Tanja S. Sobot, Vladimir I. Zivkovic, Ivan M. Srejovic, Jovana N. Jeremic, Tamara R. Nikolic Turnic, Nenad D. Ponorac, Anica M. Petkovic, Vladimir Lj. Jakovljevic, Dragan M. Djuric WIĘCEJ

Comparison of cancer patients' quality of life in Hungary and Germany - a cross-national questionnaire analysis

Johannes Thoma, Romána Zelkó, Balázs Hankó WIĘCEJ

Depressive disorders in copd patients - economic aspect

Edyta Rysiak, Izabela Prokop, Ilona Zaręba, Milena Osińska, Robert Mróz WIĘCEJ

Analysis of chronic myeloid leukemia pharmacotherapy costs in Poland

Anna Paczkowska, Krzysztof Kus, Monika Nowicka, Dorota Kopciuch, Tomasz Zaprutko, Mieczysław Ko-marnicki, Elżbieta Nowakowska WIĘCEJ

Analysis of chronic myeloid leukemia pharmacotherapy costs in Poland

Anna Paczkowska, Krzysztof Kus, Monika Nowicka, Dorota Kopciuch, Tomasz Zaprutko, Mieczysław Komarnicki, Elżbieta Nowakowska WIĘCEJ

Effective training of PhD students with evidence-based pharmacy - the use of online multi-module course

Mariusz Panczyk, Ilona Cieślak, Aleksander Zarzeka, Mariusz Jaworski, Joanna Gotlib WIĘCEJ

Access to vaccination in the greater Poland (Poland)

Tomasz Zaprutko, Dorota Kopciuch, Anna Paczkowska, Dominika Sawicka, Zuzanna Stachowiak, Patrycja Bogdaniec, Krzysztof Kus, Elżbieta Nowakowska WIĘCEJ

Acknowledgment to Reviewers 2018

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Nuclear targeting study of HPMA copolymer-5-fluorouracil conjugate based on the subcellular distribution in PC-3 cells

Lan You, Shi-Ying Dai, Yuan Huang, Li Ming Ye, Chun-Mei Fu WIĘCEJ

EPR study of free radicals formed in fusidic acid and neomycin under UV irradiation

Ewa Pierzchała, Paweł Ramos, Barbara Pilawa WIĘCEJ

Temperature dependent solubility studies of brigatinib in some pure solvents useful in dosage form develop-men

Muqtader Mohammad, Md. Khalid Anwer, Farhat Fatima, Saad M. Alshahran, Abdullah S. Alshetaili, Ahmed Alalaiwe, Bader B. Alsulays, Faiyaz Shakeel WIĘCEJ

Can angiotensin-converting enzyme inhibitors interfere with the free radicals? Measurement of antioxidant capacity using DPPH radical reduction examined by UV-Vis method

Anna Juszczak, Paweł Ramos, Wojciech Szczołko, Barbara Pilawa, Beata J. Stanisz WIĘCEJ

Determination of paracetamol in commercial suppositories using differential scanning calorimetry

Edyta Leyk, Sebastian Komar, Marek Wesołowski WIĘCEJ

Synthesis, immunosuppressive properties, mechanism of action and X-ray analysis of a new class of isoxazole derivatives

Urszula Bąchor, Stanisław Ryng, Marcin Mączyński, Jolanta Artym, Maja Kocięba, Ewa Zaczyńska, Iwona Kochanowska, Ewa Tykarska, Michał Zimecki WIĘCEJ

Synthesis and anticonvulsant properties of some n-aryl and n-arylaminomethyl derivatives of 3-p-isopropoxyphenylpyrrolidine-2,5-dione

Sergey L. Kocharov, Henry Panosyan, Jarosław Chmielewski, Barbara Gworek, Jarogniew J. Łuszczki WIĘCEJ

Fatty acids analysis and antioxidant activity of a lipid extract obtained from Mercurialis annua L. grown wildly in Jordan

Nedhal Al-Douri, Ashok K. Shakya WIĘCEJ

Validation of hepatoprotective use of Polygonum perfoliatum extract against paracetamol induced toxicity in wistar rats

Mohammad Saleem, Muhammad Fahd Mushtaq, Muhammad Furqan Akhtar, Ammara Saleem, Sara Zahid, Ali Sharif, Bushra Akhtar, Eshwa Dar, Munair Badshah, Majeed Ullah WIĘCEJ

In vitro antiviral and antioxidant activities of silymarin and Panax ginseng on vero cells infected with Bovine ephemeral fever virus and Bluetongue virus

Burak Dik, Oguzhan Avci, Irmak Dik WIĘCEJ

Antinociceptive action of Ononis spinosa leaf extract in mouse pain models

Sahar Majdi Jaffal, Manal Ahmad Abbas WIĘCEJ

Mango ginger supplementation may protect bone damage induced by methotrexate in rats

Fusun Erten, Mehmet Tuzcu, Cemal Orhan, Ibrahim Hanifi Zahid, Ali Sharif, Bushra Akhtar, Eshwa Dar, Munair Badshah, Majeed Ullah Kazim Sahin WIĘCEJ

Development and in-vitro characterization of nanoemulsion-based buccal patches of valsartan

Rana Abu-Huwaij, Rania Hamed, Enas Daoud, Ahlam Zaid Alkilani WIĘCEJ

Non-homogeneous dissolution of drug affects the quality of parenteral treatment

Pavlína Štrbová, Petra Matalová, Karel Urbánek, Martin Poruba WIĘCEJ

Release and permeation of indomethacin from phospholipid complex film generated from spray formulations

Wilaiporn Buatong, Titpawan Nakpheng, Janwit Dechraksa, Sao-Ake Saisamuth, Wipatcha Kongkhao, Teerapol Srichana WIĘCEJ

Development of tablets containing solid dispersion of ibuprofen manufactured by hot melt impregnation process

Kamil Garbera, Katarzyna Woś-Latosi, Wiesław Sawicki WIĘCEJ

A study of the combination of microcrystalline cellulose and mannitol in a co-processed dry binder and in a physical mixture for the use in orally disintegrating tabletsd

Jitka Mužikova, Andres Nowotna, Martinb Bartoš WIĘCEJ

Health behaviour of elderly patients with heart failure in Poland associated with pharmacotherapy and non-pharmacological treatment

Magdalena Makarewicz-Wujec, Ewelina Janas, Małgorzata Kozłowska-Wojciechowska WIĘCEJ

Influence of community pharmacy specialization on professional pharmaceutical counselling scheme in phar-macies in Poznan and Warsaw (Poland)–pilot study

Magdalena Waszyk-Nowaczyk, Beata Szukalska, Weronika Guzenda, Michał Michalak WIĘCEJ

Beyond clinical care: the pharmacoeconomic and research roles of pharmacists in Poland

Iga Pawłowska, Natalia Krzyżaniak, Leszek Pawłowski, Ivan Kocić WIĘCEJ

Spis treści/Contens

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Antipsychotics and low vitamin D – additional data calling for drug causality assessment

Svetlana Ristic, Dragan Milovanovic, Vladimir Janjic, Marijana Stanojevic Pirkovic, Ivana Simic Vukomanov-ic, Svetlana Curcic, Sanja Kocic WIĘCEJ

Fermented oriental medicinal insect extract has a synergistic effect on inhibiting TGF-beta1- or H2O2-induced hepatic fibrogenesis in LX-2 and HepG2 cells

Young-Ji Choi, In-Sun Park, You-Kyung Son, Kang-Yeol Yu, Jiyoung Kim, Young-Moo Choo WIĘCEJ

Applicability of the evidem multi-criteria decision analysis framework for orphan drugs – results from a stydy in 7 Eurasian countries

Aleksandra Baran-Kooiker, Kagan Atikeler, Kamilla Gaitova, Malwina Holownia-Voloskova, Adina Turcu-Stiolica, Coen Kooiker, Oresta Piniazhko, Marcin Czech WIĘCEJ

How to identify osteoporotic patients’ attitude towards pharmaceutical practice?

Edit Veszelyné Kotán, Zoltán Vincze, Ágne Mészáros WIĘCEJ

Effects of vitamin D3 and resveratrol on learning and memory disabilities of streptozotocin-induced diabetic mice

Osman Kukula WIĘCEJ

Microemulsion and microemulsion based gel of zaleplon for transdermal delivery: preparation, optimization, and evaluation

Muhammad Naeem, Zarqa Nawaz, Taniya Iqbal, Sajjad Hussain, Muhammad Yousuf, Hafiz Arfat Idrees, Atif Ali WIĘCEJ

The effects of carvacrol on oxidative stress parameters and apoptosis process via trpa1 channels in neuroblas-toma cells

Mehmet Yalcin Gunal, Ishak Suat Ovey WIĘCEJ

Tyrosinase inhibitory and antioxidant activity of wild Rosa canina L. and Sorbus aucuparia L. fruit extracts

Milica I. Stanković, Vesna Lj. Savić, Jelena V. Živković, Ljiljana P. Stanojević, Vanja M. Tadić, Ivana A. Arsić WIĘCEJ

Dose-effect relationship on anti-inflammatory activity on LPS induced raw 264.7 cells and antioxidant activity of rutin in vitro

Chunlian Tian, Yuru Guo, Yu Chang, Jihang Zhao, Cancan Cui, Mingchun Liu WIĘCEJ

Cyanidin and peonidin inhibit spca-1 growth in vitro via inducing cell cycle arrest and apoptosis

Heng Yue, Qianqian Xu, Liuzhuang Lv, Hua Fan, Jianfeng Xu, Wenhan Wang WIĘCEJ

Assessments of antioxidant content and the anti-carcinogenic effect of extracts of Solanum rostratum Dunal in human cancer cells

María del Carmen Valadez-Vega, Jeannett A. Izquierdo-Vega, Manuel Sánchez-Gutiérrez, José Roberto Vil-lagómez-Ibarra, Eduardo Osiris Madrigal Santillán, José A. Morales-González, Mirandeli Bautista-Ávila, Laura García-Velazco WIĘCEJ

Allium ursinum L. leaves components modified the physico-chemical properties of red blood cells protecting them from the effects of oxidative stress

Sylwia Cyboran-Mikołajczyk, Halina Kleszczyńska, Jan Oszmiański, Robert Pasławski WIĘCEJ

Synthesis and biological evaluation of some new pyridines, isoxazoles and isoxazolopyridazines bearing 1,2,3-triazole moiety

Huda R.M. Rashdan, Anhar Abdel-Aziem, Dina H. El-Naggar, Sara Nabil WIĘCEJ

Design, synthesis and biological estimation of innovative pyrazoles as anticancer agents targeting CDK2

Ibrahim Ali M. Radini, Diaa A. Ibrahim, Rizk E. Khidre WIĘCEJ

Analytical procedure elaboration of total flavonoid content determination and antimicrobial activity of bee bread extracts

Nataliia Hudz, Oksana Yezerska, Olga Grygorieva, Soňa Felsöciová, Ján Brindza, Piotr P. Wieczorek, Miroslava Kačániová WIĘCEJ

The radiation sterilization of imipenem and cilastatin in the solid state

Karolina Kilińska, Judyta Cielecka-Piontek, Robert Skibiński, Daria Szymanowska, Andrzej Miklaszewski, Waldemar Bednarski, Przemysław Zalewski WIĘCEJ

Determination of acyclovir in rabbit plasma by high performance liquid chromatographic (HPLC) technique

Nadia Shamshad Malik, Mahmood Ahmad, Muhammad Usman Minhas, Qandeel Khalid WIĘCEJ

Neuroprotection to counteract glaucomatous degeneration of retina; the use of citicoline

Milena Kozera, Marek Rękas WIĘCEJ

Pharmaceuticals in aquatic environment. Fate and behavior, ecotoxicology and risk assessment – A review

Barbara Gworek, Marta Kijeńska, Magdalena Zaborowska, Justyna Wrzosek, Lidia Tokarz, Jarosław Chmielewski WIĘCEJ

Gentian violet: what we know and what is ahead of us

Jędrzej Dragan, Sylwia Sulimiera Michalak WIĘCEJ

Contens

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Contens

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Safety of ombitasvir/paritaprevir/ritonavir+dasabuvir in chronic hepatitis C patients with HCV genotype 1 infection

Tomasz Tatara, Marta Dąbrowska-Bender, Aneta Duda-Zalewska, Anna Staniszewska WIĘCEJ

Off-label use of medicinal products – legal rules and practices

Janusz Jaroszyński, Aneta Mela, Marzena Furtak-Niczyporuk, Łukasz Poniatowski, Jan Dąbrowski, Anna Czajka-Bełz, Agnieszka Zimmermann, Piotr Dreher, Bartłomiej Drop, Anna Staniszewska WIĘCEJ

The radiostability of betamipron in the solid state

Karolina Kilińska, Judyta Cielecka-Piontek, Robert Skibiński, Andrzej Miklaszewski, Waldemar Bednarski, Przemysław Zalewski WIĘCEJ

Approach of the State Pharmacopeia of Ukraine to analytical procedures validation on the example of chloride ions assay in peritoneal dialysis solutions

Nataliia Hudz, Dmytro Leontiev, Piotr P. Wieczorek WIĘCEJ

Pharmacokinetic interaction after oral coadministration of clarithromycin and the tyrosine kinase inhibitor lapatinib in rats

Agnieszka Karbownik, Joanna Porażka, Anna Łuczak, Artur Teżyk, Tomasz Grabowski, Anna Wolc,Edmund Grześkowiak, Edyta Szałek WIĘCEJ

Pegylated gemcitabine and methotrexate: in vitro cytotoxicity analysis and in vivo drug release profiling to assess their enhanced blood circulation

Sumera Noreen, Muhammad Abdul Qadir, Mahmood Ahmed, Syeda Kiran Shahzadi, Muhammad Yousaf WIĘCEJ

The effect of niclosamide on the head and neck carcinoma cells survival and the expression of Wnt/beta-catenin signaling and glycolysis pathway components

Robert Kleszcz, Jarosław Paluszczak, Wanda Baer-Dubowska WIĘCEJ

Total phenolic and flavonoid contents, antioxidant and antibacterial activities of selected honeys against human pathogenic bacteria

Jelena Živković, Slavica Sunarić, Nemanja Stanković, Tatjana Mihajilov-Krstev, Ana Spasić WIĘCEJ

Eucommia ulmoides Oliv. extract regulates ages-induced injury in tubular endothelial cells via the rage-Nrf2 pathway

Jinyoung Hur, Moon Ho Do, Mina Kim, Jiwon Choi, Yoonsook Kim, Sang Keun Ha WIĘCEJ

Chemical composition, cytotoxic and antioxidant activities of Celosia trigyna L. grown in Saudi Arabia

Samy Korany El-Desouky, Ahmed Awad Abdelgawad, Ali Mohamed El-Hagrassi Usama Wahid Hawas, Young-Kyoon Kim WIĘCEJ

Cytotoxic activity of Varthemia iphionoides essential oil against various human cancer cell lines

Manal Mohammad Abbas, Manal Ahmad Abbas, Yasser Ibrahim Kandil WIĘCEJ

Surface-active agents from the group of polyoxyethylated glycerol esters of fatty acids. Part IV. Equilibrium micellar solubilization of selected lipophilic therapeutic agents (BCS class II and III) in aqueous solutions of products

Michał K. Kołodziejczyk, Michał J. Nachajski, Zbigniew Marczyński, Marian M. Zgoda WIĘCEJ

Development of hydrogel capsules for use in dual-phase topical preparations containing dihydroxyacetone and amino acids – preliminary results

Bianka Jacyna, Barbara Mikolaszek, Bartosz Maciejewski, Krzysztof Cal WIĘCEJ

Irisflorentin suppresses allergic inflammation in mast cells via reducing histamine release and production of pro-inflammatory

Yunxing Li, Fanyin Meng WIĘCEJ

JWH133, a cannabinoid receptor-2 agonist, attenuates neurological deficits and brain edema after experimental intracerebral hemorrhage in mice

Loretta O. Iniaghe, Sherrefa R. Burchell, John H. Zhang, Jiping Tang WIĘCEJ

Safety of oral nifuroxazide – analysis of data from a spontaneous reporting system

Katarzyna Karłowicz-Bodalska, Krystyna Głowacka, Kamila Boszkiewicz, Stanisław Han, Anna Wiela-Hojeńska WIĘCEJ

The effect of a single or multiple doses of grapefruit juice on some pharmacokinetic and pharmacodynamic effects of paracetamol in mice

Mohammed Al Za’abi, Asma Al-Hadhrami, Badreldin H Ali WIĘCEJ

Scoring ligand efficiency

Jaroslaw Polanski, Roksana Duszkiewicz, Anna Pedrys, Johann Gasteiger WIĘCEJ

The use of OTC herbal sedatives by pharmacy patients – a questionnaires based survey study

Adam Kowalczyk, Donata Kurpas, Agnieszka Bodalska, Stanislaw Han, Ernest Kuchar, Dominik Marciniak, Izabela Fecka, Katarzyna Karlowicz-Bodalska WIĘCEJ

Pełna wersja czasopisma/The entire magazine

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